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Anti-Human GDF-8/Myostatin Reference Antibody (Landogrozumab, RUO)
Overview
Catalog No. HT343016
Brand abinScience
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Isotype IgG4-kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession O14793
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameLY-2495655, 1391726-30-9
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Images


Bioactivity
SEC-HPLC detection for Research Grade Landogrozumab.

Flow Cytometry
Flow-cytometry using anti-human MSTN antibody. LNCAP cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human MSTN monoclonal antibody (Catalog HT343016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

SDS-PAGE
SDS-PAGE for Research Grade Landogrozumab