Anti-Human IL-6R alpha/IL6R Reference Antibody (Sarilumab, RUO)

Catalog No.

HY583016

Brand

abinScience

Host species

Human

Tested applications

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Purity

>95% as determined by SDS-PAGE.

Clonality

Monoclonal

Isotype

IgG1-kappa

Applications

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

Target

CD126, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6R, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, Soluble interleukin-6 receptor subunit alpha, gp80, sIL6R

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

< 10 EU/mg as determined by LAL method.

Accession

P08887

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative name

REGN88, SAR153191, 1189541-98-7

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

SEC-HPLC	SEC-HPLC detection for Research Grade Sarilumab.
Bioactivity	Detects Human CD126/IL6R/IL-6RA in indirect ELISAs.
SDS-PAGE	SDS-PAGE for Anti-Human IL-6R alpha/IL6R Reference Antibody (Sarilumab, RUO)
Western blot	Western blot analysis was performed using anti-CD126/IL6RA monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human CD126/IL6RA (Catalog No: HY583011) Lane 2: negative control