Anti-Ganglioside GD2 Reference Antibody (Morab-028, RUO)

Catalog No.	YP115056
Brand	abinScience
Host species	Human
Species reactivity	General
Form	Liquid
Storage buffer	0.01M PBS pH 7.4
Purity	>95% purity as determined by SDS-PAGE.
Clonality	Monoclonal
Isotype	IgG1
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target	Ganglioside GD2
References	1. Nazha B, et al. Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy. Front Oncol. 2020;10:1000. Published 2020 Jul 7. [YP115056] 2. Erber R, et al. Variable Expression of the Disialoganglioside GD2 in Breast Cancer Molecular Subtypes. Cancers (Basel). 2021;13(21):5577. Published 2021 Nov 8. [YP115056]
Purification	Protein A/G purified from cell culture supernatant.
Biological activity	Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action involves enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on tumor type [1].
Endotoxin level	< 10 EU/mg
Expression system	Mammalian cells
Accession	CAS: 65988-71-8
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative name	MORAb-028, MT228
Note	For research use only. Not suitable for clinical or therapeutic use.