Anti-Human BCMA/TNFRSF17 & CD3 epsilon Bispecific Reference Antibody (Pavurutamab, RUO)
Overview
| Catalog No. |
HX959056 |
| Brand |
abinScience |
| Tested applications |
FCM |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Isotype |
(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD269, B-cell maturation protein, BCMA, BCM, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
Q02223 & P07766 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | Bispecific, AMG-701, BCMAHLE-BiTE, 2250292-39-6 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control |
Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Pavurutamab |
 Flow cytometry |
Flow-cytometry using anti-human CD269 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD269 monoclonal antibody (Catalog HX959056) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, AF647 (abinScience: HF690324) and cells analysed on a NovoCyte Flow Cytometer. |