Anti-Human PD-L1 & CD47 Bispecific Reference Antibody (Simridarlimab, RUO)

Catalog No.

HC359056

Brand

abinScience

Tested applications

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Purity

>95% purity as determined by SDS-PAGE.

Isotype

(G1_L-kappa)_VH-VH-h-CH2-CH3

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Target

B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

< 10 EU/mg

Expression system

Mammalian cells

Accession

Q9NZQ7 & Q08722

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative name

Bispecific, IBI322, IBI-322, IBI3222378862-90-7

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

SDS-PAGE	SDS-PAGE for Research Grade Simridarlimab.
Bioactivity	Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot	Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human PDL1 (Catalog No: HV974011) Lane 2: Negative control