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Anti-Human CD15/Lewis X Reference Antibody (Fanolesomab, RUO)
Overview
Catalog No. HB132016
Brand abinScience
Host species Mouse
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG2a, kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target Alpha-(1, 3)-fucosyltransferase 4, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase, Fuc-TIV, FCT3A, FUT4, ELFT, FucT-IV
References 1. Klingensmith WC 3rd, et al. Intrapatient comparison of 2-deoxy-2-[F-18]fluoro-D-glucose with positron emissiontomography/computed tomography to Tc-99m fanolesomab (NeutroSpec) for localization of infection. Mol Imaging Biol. 2007;9(5):295-299. [HB132016]
Purification Protein A/G purified from cell culture supernatant.
Biological activity Fanolesomab uses a technetium-99m label, enables white blood cell labeling, eliminates need for handling blood products, and is readily available. Fanolesomab exhibits 100% specificity in infection imaging [1].
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession P22083
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameFanolesomab
Note For research use only. Not suitable for clinical or therapeutic use.
Images


Bioactivity
SEC-HPLC detection for Research Grade Fanolesomab.

SDS-PAGE
SDS-PAGE for Research Grade Fanolesomab.