| Catalog No. | HW444076 |
| Brand | abinScience |
| Host species | Human |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | CKR-L1, CMKBR8, C-C CKR-8, GPR-CY6, CCR8, CMKBRL2, TER1, CCR-8, Chemokine receptor-like 1, CKRL1, CDw198, GPRCY6, C-C chemokine receptor type 8, CC-CKR-8, CC chemokine receptor CHEMR1 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | CM369 can bind to CCR8 on the surface of CCR8-positive tumor-infiltrating regulatory T cells within the tumor microenvironment and deplete these cells via antibody-dependent cell-mediated cytotoxicity (ADCC), thereby potentially reactivating the anti-tumor immune response. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | P51685 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | CM369 |
| Clone ID | CM369 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Anti-Human CCR8 Reference Antibody (CM369, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human CD198/CCR8 (CM369) |