| Catalog No. | HB103066 |
| Brand | abinScience |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Isotype | IgG1 |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B |
| References | 1. Rieth N, et al. Characterization of SM201, an anti-hFcγRIIB antibody not interfering with ligand binding that mediates immune complex dependent inhibition of B cells. Immunol Lett. 2014;160(2):145-150. [HB103066] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | SM201 (5 ug/mL) specifically binds to Fc-RIIB on Raji cells and shows no cross-reactivity with Fc-RIIA on K-562 cells [1]. SM201 (0.01-10 ug/mL; 1 h) does not interfere with the binding of IgG to Fc-RIIB on Raji cells [1]. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | P31994 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | SM201 |
| Clone ID | SM201 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Anti-Human Fc gamma RIIB/CD32b Reference Antibody (SM201, RUO)
Overview
Images
 Bioactivity |
Detects CD32b/FCGR2B in indirect ELISAs. |
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human CD32b/FCGR2B (SM201). |