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Anti-Human CD27 Ligand/TNFSF7/CD70 Reference Antibody (AMG 172, RUO)
Overview
Catalog No. HW717036
Brand abinScience
Host species Human
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L
References 1. Massard C, et al. First-in-human study to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of the anti-CD27L antibody-drug conjugate AMG 172 in patients with relapsed/refractory renal cell carcinoma. Cancer Chemother Pharmacol. 2019;83(6):1057-1063. [HW717036]
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession P32970
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameAMG-172, AMG172, AMG172
Clone IDAMG 172
Note For research use only. Not suitable for clinical or therapeutic use.
Images


SDS-PAGE
SDS-PAGE for Research Grade Anti-Human CD70 (AMG 172)