Anti-Human Claudin-18.2 Reference Antibody (GB7004-09, RUO)
Overview
| Catalog No. |
HX126146 |
| Brand |
abinScience |
| Host species |
Human |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Clonality |
Monoclonal |
| Isotype |
IgG |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
Claudin-18, CLDN18 |
| References |
1. Zhenhao Zhou. Abstract 340: Development of high affinity anti-CLDN18.2 antibody to treat gastric cancers. Cancer Res 1 July 2019; 79 (13_Supplement): 340. [HX126146] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Biological activity |
GB7004-09 exhibits superior binding affinity, antibody-dependent cell-mediated cytotoxicity, and complement-dependent cytotoxicity against CLDN18.2-expressing tumor cells [1]. CLDN18. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
P56856 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | GB7004-09, GB700409, GB700409 |
| Clone ID | GB7004-09 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human CLDN18.2 (GB7004-09) |