下载
Anti-Human EGFR Reference Antibody (MM-151, RUO)
Overview
Catalog No. HF004376
Brand abinScience
Host species Human
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4.
Purity >95% as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG
Applications ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Target EC:2.7.10.1, EGFR, ERBB, ERBB1, Epidermal growth factor receptor, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
References 1. Arena S, et al. MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations. Sci Transl Med. 2016 Feb 3;8(324):324ra14. [HF004376]
2. Kearns JD, et al. Enhanced Targeting of the EGFR Network with MM-151, an Oligoclonal Anti-EGFR Antibody Therapeutic. Mol Cancer Ther. 2015 Jul;14(7):1625-36. [HF004376]
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Accession P00533
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameMM-151, MM151, MM151
Clone IDMM-151
Note For research use only. Not suitable for clinical or therapeutic use.
Images


SDS-PAGE
SDS-PAGE for Research Grade Anti-Human EGFR/ERBB1/HER1 (MM-151)