| Catalog No. | HX148016 |
| Brand | abinScience |
| Host species | Human |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG1-kappa |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Target | Tyrosine-protein kinase receptor SEK, Tyrosine-protein kinase TYRO1, Ephrin type-A receptor 4, TYRO1, EPHA4, EPH-like kinase 8, hEK8, SEK, EK8, HEK8 |
| References | 1. Garrido-Laguna I, et al. First-in-human, phase I study of PF-06647263, an anti-EFNA4 calicheamicin antibody-drug conjugate, in patients with advanced solid tumors. Int J Cancer. 2019 Oct 1;145(7):1798-1808. [HX148016] 2. Damelin M, et al. Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions. Clin Cancer Res. 2015 Sep 15;21(18):4165-73. [HX148016] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Expression system | Mammalian cells |
| Accession | P54764 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | PF-06647263, PF06647263, PF06647263 |
| Clone ID | PF-06647263 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107) |
Anti-Human EphA4 Reference Antibody (PF-06647263, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human EPHA4 (PF-06647263) |