Anti-Human EGFRvIII & PD-L1 & 4-1BB/TNFRSF9/CD137 & CD3 epsilon Multispecific Reference Antibody (Umizortamig, RUO)

Catalog No.

HF004466

Brand

abinScience

Tested applications

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Purity

>95% purity as determined by SDS-PAGE.

Isotype

immunoglobulin scFv-G1-scFv-scFv_L-kappa

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Target

HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

< 10 EU/mg

Expression system

Mammalian cells

Accession

P00533 & P07766 & Q9NZQ7 & Q07011

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative name

2599198-83-9

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Note

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

SDS-PAGE	SDS-PAGE for Research Grade Umizortamig.
Bioactivity	Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Bioactivity	Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Bioactivity	Detects recombinant ERBB1 (Catalog No: HF004011) in indirect ELISA.
Western blot	Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human CD3E (Catalog No: HY057021)