| Catalog No. | HV678016 |
| Brand | abinScience |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Isotype | IgG1-kappa |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | IL-31, Interleukin-31, IL31 |
| References | 1. Tietz J, et al. A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis. JID Innov. 2024;4(2):100258. Published 2024 Jan 16. [HV678016] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | BMS-981164 (0.01-10000 pM; 6 h) inhibits the IL-31 signaling pathway in a dose-dependent manner in PathHunter U2OS IL31RA/OSMR dimerization cells [1]. BMS-981164 (5 nM; 24 h) inhibits IL-4/IL-31-induced CCL2 secretion in human bronchial epithelial BEAS-2B cells [1]. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | Q6EBC2 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | BMS-981164, BMS981164, BMS981164 |
| Clone ID | BMS-981164 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Anti-Human IL-31 Reference Antibody (BMS-981164, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human IL31 (BMS-981164). |
 Bioactivity |
Detects Recombinant Human IL31 Protein, C-His (Cat No.: HV678011) in indirect ELISA. |