Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (REGN6490, RUO)
Overview
| Catalog No. |
HV045016 |
| Brand |
abinScience |
| Host species |
Human |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Clonality |
Monoclonal |
| Isotype |
IgG4, kappa |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
IL1R-rp2, IL1RL2, IL1RRP2, IL-1Rrp2, IL-36 receptor, Interleukin-1 receptor-related protein 2, Interleukin-1 receptor-like 2, IL-36R |
| References |
1. Jason E Hawkes, et al. The role of the interleukin-36 axis in generalized pustular psoriasis: a review of the mechanism of action of spesolimab. Front Immunol. 2023 Nov 21:14:1292941. [HV045016] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
Q9HB29 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | REGN6490 |
| Clone ID | REGN6490 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human IL1RL2/IL-36R (REGN6490) |