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Anti-Human IL-4R alpha Reference Antibody (AMG 317, RUO)
Overview
Catalog No. HB732056
Brand abinScience
Host species Human
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target IL-4RA, IL-4-binding protein, IL-4 receptor subunit alpha, Soluble IL-4R-alpha, IL4-BP, IL4R, IL-4R subunit alpha, IL-4R-alpha, CD124, Interleukin-4 receptor subunit alpha, IL4RA, Soluble IL-4 receptor subunit alpha, sIL4Ralpha/prot
References 1. Jonathan Corren, et al. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med. 2010 Apr 15;181(8):788-96. [HB732056]
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession P24394
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameAMG-317, AMG317, AMG317
Clone IDAMG 317
Note For research use only. Not suitable for clinical or therapeutic use.
Images


SDS-PAGE
SDS-PAGE for Research Grade Anti-Human CD124/IL4R/IL-4Rα (AMG 317)