Anti-Human IL-4R alpha Reference Antibody (AMG 317, RUO)
Overview
| Catalog No. |
HB732056 |
| Brand |
abinScience |
| Host species |
Human |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Clonality |
Monoclonal |
| Isotype |
IgG |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
IL-4RA, IL-4-binding protein, IL-4 receptor subunit alpha, Soluble IL-4R-alpha, IL4-BP, IL4R, IL-4R subunit alpha, IL-4R-alpha, CD124, Interleukin-4 receptor subunit alpha, IL4RA, Soluble IL-4 receptor subunit alpha, sIL4Ralpha/prot |
| References |
1. Jonathan Corren, et al. A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am J Respir Crit Care Med. 2010 Apr 15;181(8):788-96. [HB732056] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
P24394 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | AMG-317, AMG317, AMG317 |
| Clone ID | AMG 317 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human CD124/IL4R/IL-4Rα (AMG 317) |