Anti-Human LAG-3 Reference Antibody (GSK2831781, RUO)
Overview
| Catalog No. |
HB613166 |
| Brand |
abinScience |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Isotype |
IgG1-kappa |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
FDC, LAG3, Lymphocyte activation gene 3 protein, CD223, sLAG-3, LAG-3 |
| References |
1. D'Haens G, et al. A randomised, double-blind, placebo-controlled study of the LAG-3-depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis. Aliment Pharmacol Ther. 2023 Aug;58(3):283-296. [HB613166] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
P18627 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | GSK2831781 |
| Clone ID | GSK2831781 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control |
Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Images
 SDS-PAGE |
SDS-PAGE for Anti-Human LAG-3 Reference Antibody (GSK2831781, RUO) |
 Bioactivity |
Detects recombinant human CD223/LAG3 (Catalog No: HB613011) in indirect ELISA |