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Anti-Human LAG-3 Reference Antibody (GSK2831781, RUO)
Overview
Catalog No. HB613166
Brand abinScience
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Isotype IgG1-kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target FDC, LAG3, Lymphocyte activation gene 3 protein, CD223, sLAG-3, LAG-3
References 1. D'Haens G, et al. A randomised, double-blind, placebo-controlled study of the LAG-3-depleting monoclonal antibody GSK2831781 in patients with active ulcerative colitis. Aliment Pharmacol Ther. 2023 Aug;58(3):283-296. [HB613166]
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession P18627
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameGSK2831781
Clone IDGSK2831781
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images


SDS-PAGE
SDS-PAGE for Anti-Human LAG-3 Reference Antibody (GSK2831781, RUO)

Bioactivity
Detects recombinant human CD223/LAG3 (Catalog No: HB613011) in indirect ELISA