Anti-Human OX40 Ligand/TNFSF4 Reference Antibody (GSK 3174998, RUO)
Overview
| Catalog No. |
HW342146 |
| Brand |
abinScience |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Isotype |
IgG |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134 |
| References |
1. Postel-Vinay S, et al. First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1). J Immunother Cancer. 2023 Mar;11(3):e005301. [HW342146] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
P43489 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | GSK-3174998, GSK3174998, GSK3174998 |
| Clone ID | GSK 3174998 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control |
Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human CD134/TNFRSF4/OX40 (GSK 3174998) |
 Bioactivity |
Detects recombinant human CD134/TNFRSF4/OX40 (Catalog No: HW342011) in indirect ELISA |