| Catalog No. | HB727026 |
| Brand | abinScience |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Isotype | IgG4, kappa |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | S100A4, Protein S100-A4, S100 calcium-binding protein A4, Calvasculin, Protein Mts1, MTS1, CAPL, Placental calcium-binding protein, Metastasin |
| References | 1. Trinh-Minh T, et al. Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin. Arthritis Rheumatol. 2024;76(5):783-795. [HB727026] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | AX-202 (8-16 mg/kg, i.p., once every 3 days for 3 weeks; 24 mg/kg, i.v., once weekly for 3 weeks) exhibits antifibrotic and anti-inflammatory effects in a bleomycin ()-induced skin fibrosis model [1]. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | P26447 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | AX-202, AX202, CAL101 |
| Clone ID | AX-202 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
Anti-Human S100A4 Reference Antibody (AX-202, RUO)
Overview
Images
