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Anti-Human Tau Reference Antibody (APNmAb005, RUO)
Overview
Catalog No. HY086076
Brand abinScience
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Isotype IgG4, kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target MAPTL, Paired helical filament-tau, MTBT1, Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, MAPT, PHF-tau
References 1. Tai C Y, et al. APNmAb005, an anti‐tau antibody targeting synaptic tau oligomers, in Phase 1 for treatment of Alzheimer’s Disease and primary tauopathies[J]. Alzheimer's & Dementia, 2023, 19: e076888. [HY086076]
Purification Protein A/G purified from cell culture supernatant.
Biological activity and rescues neuronal loss in rTG4510 mice. APNmAb005 can be used in Alzheimer’s disease (AD) research [1].
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession P10636
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameAPNmAb005
Clone IDAPNmAb005
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)
Images


SDS-PAGE
SDS-PAGE for Research Grade Anti-Human MAPT/Tau/PHF-tau (APNmAb005)