| Catalog No. | HY086076 |
| Brand | abinScience |
| Host species | Human |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. |
| Purity | >95% as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG4, kappa |
| Applications | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| Target | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU |
| References | 1. Tai C Y, et al. APNmAb005, an anti‐tau antibody targeting synaptic tau oligomers, in Phase 1 for treatment of Alzheimer’s Disease and primary tauopathies[J]. Alzheimer's & Dementia, 2023, 19: e076888. [HY086076] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | and rescues neuronal loss in rTG4510 mice. APNmAb005 can be used in Alzheimer’s disease (AD) research [1]. |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Accession | P10636 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | APNmAb005 |
| Clone ID | APNmAb005 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
Anti-Human Tau Reference Antibody (APNmAb005, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human MAPT/Tau/PHF-tau (APNmAb005) |