Anti-Human Tau Reference Antibody (APNmAb005, RUO)
Overview
| Catalog No. |
HY086076 |
| Brand |
abinScience |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS pH 7.4 |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Isotype |
IgG4, kappa |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
MAPTL, Paired helical filament-tau, MTBT1, Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, MAPT, PHF-tau |
| References |
1. Tai C Y, et al. APNmAb005, an anti‐tau antibody targeting synaptic tau oligomers, in Phase 1 for treatment of Alzheimer’s Disease and primary tauopathies[J]. Alzheimer's & Dementia, 2023, 19: e076888. [HY086076] |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Biological activity |
and rescues neuronal loss in rTG4510 mice. APNmAb005 can be used in Alzheimer’s disease (AD) research [1]. |
| Endotoxin level |
< 10 EU/mg |
| Expression system |
Mammalian cells |
| Accession |
P10636 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | APNmAb005 |
| Clone ID | APNmAb005 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control |
Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human MAPT/Tau/PHF-tau (APNmAb005) |