| Catalog No. | HV571056 |
| Brand | abinScience |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Isotype | IgG |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 |
| References | 1. Jenkins DW, et al. MEDI0639: a novel therapeutic antibody targeting Dll4 modulates endothelial cell function and angiogenesis in vivo. Mol Cancer Ther. 2012 Aug;11(8):1650-60. [HV571056] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | MEDI0639 promotes human angiogenesis and reduces the number of vessels covered by smooth muscle actin-positive mural cells. MEDI0639 can be used in Small cell lung cancer and solid tumors research [1]. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | Q9NR61 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | MEDI0639 |
| Clone ID | MEDI0639 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1, lambda Isotype Control antibody (HyHEL-10) (HP248107) |
Anti-Human DLL4 Reference Antibody (MEDI0639, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-Human DLL4 (MEDI0639) |