Anti-Candida auris β-1, 3 glucans Reference Antibody (2G8, RUO)

Catalog No.	JN903016
Brand	abinScience
Host species	Human
Species reactivity	Candida auris
Form	Liquid
Storage buffer	0.01M PBS pH 7.4
Purity	>95% purity as determined by SDS-PAGE.
Clonality	Monoclonal
Isotype	IgG1, kappa
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target	Cryptococcus neoformans, β-D-glucan, Beta-D-Glucan, beta-Glucan, β-1, 3 glucans
References	1. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. [JN903016] 2. Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. [JN903016] 3. Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44(4):1365-1375. [JN903016]
Purification	Protein A/G purified from cell culture supernatant.
Biological activity	β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC 50 of ～164 ug/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC 50 values of 4.6 and 24.2 ug/mL, respectively [3].
Endotoxin level	< 10 EU/mg
Expression system	Mammalian cells
Accession	ChEBI: 28793, 9041-22-9
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Clone ID	2G8
Note	For research use only. Not suitable for clinical or therapeutic use.