Anti-Human CEACAM-5/CD66e & CD3 epsilon Bispecific Reference Antibody (MEDI-565, RUO)

Catalog No.

HY546126

Brand

abinScience

Host species

Human

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Purity

>95% purity as determined by SDS-PAGE.

Clonality

Monoclonal

Isotype

BiTE

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Target

Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5, CEA, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E

References

1. Moek KL, et al. 89Zr-labeled Bispecific T-cell Engager AMG 211 PET Shows AMG 211 Accumulation in CD3-rich Tissues and Clear, Heterogeneous Tumor Uptake. Clin Cancer Res. 2019 Jun 15;25(12):3517-3527. [HY546126]

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

< 10 EU/mg

Expression system

Mammalian cells

Accession

P06731 & P07766

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative name

Bispecific, AMG-211, AMG211, AMG211, MT-111, MT111, MT111, MEDI565, MEDI565

Clone ID

MEDI-565

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Note

For research use only. Not suitable for clinical or therapeutic use.