| Catalog No. | VK421266 |
| Brand | abinScience |
| Host species | Human |
| Species reactivity | Human respiratory syncytial virus A (HRSV-A) |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 |
| Purity | >95% purity as determined by SDS-PAGE. |
| Isotype | IgG1 |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | F, Fusion glycoprotein F0, Prefusion, Pre-F |
| References | 1. Scotta MC, et al. Current strategies and perspectives for active and passive immunization against Respiratory Syncytial Virus in childhood. J Pediatr (Rio J). 2023;99 Suppl 1(Suppl 1):S4-S11. [VK421266] |
| Purification | Protein A/G purified from cell culture supernatant. |
| Biological activity | RSM-01 tightly binds to the highly conserved Ø site on the Pre-F protein, blocks viral conformational changes, inhibits viral fusion with host cell membranes, and prevents viral entry into cells. It exhibits ultra-high neutralizing activity against both RSV subtype A and subtype B [1]. |
| Endotoxin level | < 10 EU/mg |
| Expression system | Mammalian cells |
| Accession | P03420 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | RSM-01, RSM01, RSM01 |
| Clone ID | RSM01 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Anti-HRSV Pre-Fusion Glycoprotein Reference Antibody (RSM01, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Anti-HRSV Prefusion/Pre-F Antibody (RSM01) |