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Anti-HRSV Pre-Fusion Glycoprotein Reference Antibody (RSM01, RUO)
Overview
Catalog No. VK421266
Brand abinScience
Host species Human
Species reactivity Human respiratory syncytial virus A (HRSV-A)
Form Liquid
Storage buffer 0.01M PBS pH 7.4.
Purity >95% as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG1
Applications ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Target F, F1, F2, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Intervening segment, Pep27, Peptide 27, p27
References 1. Scotta MC, et al. Current strategies and perspectives for active and passive immunization against Respiratory Syncytial Virus in childhood. J Pediatr (Rio J). 2023;99 Suppl 1(Suppl 1):S4-S11. [VK421266]
Purification Protein A/G purified from cell culture supernatant.
Biological activity RSM-01 tightly binds to the highly conserved Ø site on the Pre-F protein, blocks viral conformational changes, inhibits viral fusion with host cell membranes, and prevents viral entry into cells. It exhibits ultra-high neutralizing activity against both RSV subtype A and subtype B [1].
Endotoxin level < 10 EU/mg
Accession P03420, P11209, 12568, O36634, P13843
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameRSM-01, RSM01, RSM01
Clone IDRSM01
Note For research use only. Not suitable for clinical or therapeutic use.
Images


SDS-PAGE
SDS-PAGE for Research Grade Anti-HRSV Prefusion/Pre-F Antibody (RSM01)