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Anti-HIV-1 gp120 120 Reference Antibody (VRC01LS, RUO)
Overview
Catalog No. VK617066
Brand abinScience
Host species Human
Species reactivity Human immunodeficiency virus type 1 (HIV-1)
Form Liquid
Storage buffer 0.01M PBS pH 7.4
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target gp120/Glycoprotein 120
References 1. Happe M, et al. Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection. JCI Insight. 2025 Feb 24;10(4):e181496. [VK617066]
2. Gaudinski MR, et al. Safety and pharmacokinetics of the Fc-modified HIV-1 human monoclonal antibody VRC01LS: A Phase 1 open-label clinical trial in healthy adults. PLoS Med. 2018 Jan 24;15(1):e1002493. [VK617066]
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level < 10 EU/mg
Expression system Mammalian cells
Accession Q03805
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative nameVRC01LS
Clone IDVRC01LS
Note For research use only. Not suitable for clinical or therapeutic use.
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Bioactivity
Detects recombinant HIV1 gp120 (Catalog No: VK617011) in indirect ELISA.

Bioactivity
Detects recombinant HIV1 gp120 (Catalog No: VK617021) in indirect ELISA.