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(Recent 2026 articles on SARS-CoV-2 boosters, MDA5, and IL-22/niche in mucosal immunity)

Nature Immunology

Updated SARS-CoV-2 boosters broaden humoral immunity by recalling cross-reactive antibodies and eliciting new less cross-reactive Omicron type-specific antibodies that target distinct RBD epitopes and more potently neutralize recent variants. MDA5 detects double-stranded RNA during viral infections. This work shows that MDA5 binds aberrant host RNA induced during viral infection. Rescue of aberrant cytoplasmic RNA during infection abrogated MDA5 activation.

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(Recent 2026 articles on SARS-CoV-2 boosters, MDA5, and IL-22/niche in mucosal immunity)