

| 货号 | MB123019 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
InVivo Plus Anti-Mouse NKG2D/CD314 Antibody(CX5) (MB123019) is a rat monoclonal antibody detecting NKG2D/CD314 in Blocking, ELISA, FCM. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||
| 应用 | Blocking, ELISA, FCM | ||||
| 宿主 | Rat | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG1 kappa | ||||
| 克隆号 | CX5 | ||||
| 靶标 | NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d | ||||
| 内毒素水平 | < 1 EU/mg as determined by LAL method. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 相关产品 | pH 7.4 Dilution Buffer | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | O54709 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||
| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~25 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF. | ||||
| Note | For research use only. | ||||
| Isotype Control | Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407) |

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