

| 货号 | HV721818 |
|---|---|
| 品牌 | abinScience |
| 描述 |
HEK293T Human VTCN1/B7-H4 Stable Cell Line (HV721818) is a stable cell line expressing VTCN1/B7-H4. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Accession号 | Q7Z7D3 |
| 应用 | FCM |
| 种属 | Human |
| 靶标 | VTCN1/B7-H4 |
| 性能 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 稳定性和存储 | Frozen in liquid nitrogen. |
| 规格 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | V-set domain-containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human B7H4 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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