

| 货号 | HW606818 |
|---|---|
| 品牌 | abinScience |
| 描述 |
HEK293T Human CD183/CXCR3 Stable Cell Line (HW606818) is a stable cell line expressing CD183/CXCR3. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Accession号 | P49682 |
| 应用 | FCM |
| 种属 | Human |
| 靶标 | CD183/CXCR3 |
| 性能 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 稳定性和存储 | Frozen in liquid nitrogen. |
| 规格 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. 1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716 |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD183 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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