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HEK293T Human CD158k/KIR3DL2 Stable Cell Line (HW633818)

价格:
规格:
  • 1 ml
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HW633818
品牌abinScience
描述
HEK293T Human CD158k/KIR3DL2 Stable Cell Line (HW633818) is a stable cell line expressing CD158k/KIR3DL2. Engineered for consistent, high-level target expression in research applications.
Highlights
  • Stable Expression — Engineered for consistent, high-level target expression.
Accession号P43630
应用FCM
种属Human
靶标CD158k/KIR3DL2
性能Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
稳定性和存储Frozen in liquid nitrogen.
规格1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
背景

Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.

1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270
2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952
3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
图片
  • Flow cytometry

    Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human KIR3DL2 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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