

| 货号 | HW633818 |
|---|---|
| 品牌 | abinScience |
| 描述 |
HEK293T Human CD158k/KIR3DL2 Stable Cell Line (HW633818) is a stable cell line expressing CD158k/KIR3DL2. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Accession号 | P43630 |
| 应用 | FCM |
| 种属 | Human |
| 靶标 | CD158k/KIR3DL2 |
| 性能 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 稳定性和存储 | Frozen in liquid nitrogen. |
| 规格 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464 |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human KIR3DL2 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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