

| 货号 | HW634818 |
|---|---|
| 品牌 | abinScience |
| 描述 |
HEK293T Human CD194/CCR4 Stable Cell Line (HW634818) is a stable cell line expressing CD194/CCR4. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Accession号 | P51679 |
| 应用 | FCM |
| 种属 | Human |
| 靶标 | CD194/CCR4 |
| 性能 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 稳定性和存储 | Frozen in liquid nitrogen. |
| 规格 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | C-C chemokine receptor type 4 (CD194/CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD194 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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