注册
CN
首页 > 特色产品 > 稳转细胞株

HEK293T Human CD184/CXCR4 Stable Cell Line (HX206818)

价格:
规格：
  • 1 ml
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HX206818
品牌abinScience
描述
HEK293T Human CD184/CXCR4 Stable Cell Line (HX206818) is a stable cell line expressing CD184/CXCR4. Engineered for consistent, high-level target expression in research applications.
Highlights
  • ●Stable Expression — Engineered for consistent, high-level target expression.
Accession号P61073
应用FCM
种属Human
靶标CD184/CXCR4
检测方法Colorimetric
样本类型Plasma, Serum
实验类型Quantitative
检测范围1.56 - 100 ng/mL
灵敏度0.25 ng/mL
回收率80-120%
性能Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
运输2-8 ℃
稳定性和存储Frozen in liquid nitrogen.
规格1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
背景

C-X-C chemokine receptor type 4 (CD184/CXCR4) is a ~39 kDa protein. Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. CXCR4 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g.

1. Brelot, A. et al. (1999) Journal of virology 73, 2576-86. PMID: 10074102
2. Gupta, SK. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 163, 2368-72. PMID: 10452968
3. Cheng, ZJ. et al. (2000) The Journal of biological chemistry 275, 2479-85. PMID: 10644702
4. Brelot, A. et al. (2000) The Journal of biological chemistry 275, 23736-44. PMID: 10825158
5. Veldkamp, CT. et al. (2008) Science signaling 1, ra4. PMID: 18799424
6. Busillo, JM. et al. (2010) The Journal of biological chemistry 285, 7805-17. PMID: 20048153
7. Malik, R. et al. (2010) Molecular biology of the cell 21, 2529-41. PMID: 20505072
8. Cao, Y. et al. (2015) Leukemia 29, 169-76. PMID: 24912431
9. Lear, T. et al. (2017) American journal of physiology. Cell physiology 313, C584-C592. PMID: 28978524
10. Bleul, CC. et al. (1996) Nature 382, 829-33. PMID: 8752280
NoteFor research use only. This stable cell line expresses GFP as a reporter marker. GFP is expressed independently of the target protein and is not fused to the target protein.
图片

  • Flow cytometry

    Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CXCR4 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

HEK293T Human CD184/CXCR4 Stable Cell Line

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2