

| 货号 | HB735818 |
|---|---|
| 品牌 | abinScience |
| 描述 |
HEK293T Mouse CD46 Stable Cell Line (HB735818) is a stable cell line expressing CD46. Engineered for consistent, high-level target expression in research applications.
Highlights
|
| Accession号 | P15529 |
| 应用 | FCM |
| 种属 | Mouse |
| 靶标 | CD46 |
| 检测方法 | Colorimetric |
| 样本类型 | Plasma, Serum |
| 实验类型 | Quantitative |
| 检测范围 | 1.56 - 100 ng/mL |
| 灵敏度 | 0.25 ng/mL |
| 回收率 | 80-120% |
| 性能 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 运输 | 2-8 ℃ |
| 稳定性和存储 | Frozen in liquid nitrogen. |
| 规格 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 背景 | Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. |
| Note | For research use only |

Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD46 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.



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