

| 货号 | HP986013 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 种属反应性 | Human | ||||||
| 应用 | ELISA, WB | ||||||
| 宿主 | Mouse | ||||||
| 克隆类型 | Monoclonal | ||||||
| 同种型 | IgG2a | ||||||
| 克隆号 | SAA1465 | ||||||
| 靶标 | Chemokine-like protein TAFA-5, TAFA5, FAM19A5 | ||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||||
| Accession号 | Q7Z5A7 | ||||||
| RRID | Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (abinScience Cat# HP986013, RRID:AB_3727121) | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Chemokine-like protein TAFA-5 (TAFA5/FAM19A5) is a ~14 kDa protein. Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling. | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TAFA5/FAM19A5 Antibody (SAA1465)



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