Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

VK661013

abinScience

种属反应性

Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

ELISA, WB

Human

Monoclonal

VP35, Polymerase cofactor VP35, Ebola VP35, eVP35

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q05127

Anti-ZEBOV VP35/Polymerase cofactor VP35 Antibody (F9) (abinScience Cat# VK661013, RRID:AB_3727248)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Polymerase cofactor VP35 is a ~37 kDa protein. Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes. Part of the external layer of the nucleocapsid, likely tethering the nucleocapsid to the matrix and membrane. Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1.

1. Basler, CF. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 12289-94. PMID: 11027311

2. van Tol, S. et al. (2022) PLoS pathogens 18, e1010532. PMID: 35533195

3. Enterlein, S. et al. (2006) Antimicrobial agents and chemotherapy 50, 984-93. PMID: 16495261

4. Brown, CS. et al. (2014) Journal of molecular biology 426, 2045-58. PMID: 24495995

5. Mühlberger, E. et al. (1999) Journal of virology 73, 2333-42. PMID: 9971816

6. Watanabe, R. et al. (2024) Cell 187, 5587-5603.e19. PMID: 39293445

7. Luthra, P. et al. (2015) Journal of virology 89, 5148-53. PMID: 25741013

8. Leung, DW. et al. (2015) Cell reports 11, 376-89. PMID: 25865894

9. Yen, BC. et al. (2016) Journal of virology 90, 5108-5118. PMID: 26962215

10. Luthra, P. et al. (2013) Cell host & microbe 14, 74-84. PMID: 23870315

For research use only.

SDS-PAGE

SDS-PAGE for Anti-ZEBOV VP35/Polymerase cofactor VP35 Antibody (F9)

产品说明书

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

概述

图片

参考文献

产品说明书

相关产品推荐

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