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Anti-Human ADRB3 Recombinant Antibody (SAA1577) (HB002013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HB002013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1577
靶标Beta-3 adrenoreceptor, Beta-3 adrenoceptor, B3AR, ADRB3, Beta-3 adrenergic receptor, ADRB3R
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P13945
RRIDAnti-Human ADRB3 Antibody (SAA1577) (abinScience Cat# HB002013, RRID:AB_3727338)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Beta-3 adrenergic receptor (ADRB3) is a ~43 kDa protein. G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively. The rank order of potency for physiological agonists is norepinephrine > epinephrine. Involved in the regulation of thermogenesis and lipolysis in brown and white adipose tissue, after coupling to G(s) proteins and stimulation of the cAMP-PKA axis. Also activates lipolytic process by coupling to G(i) proteins and consequent initiation of the ERK1/2 MAP kinase cascade. Participates in relaxation of the blood vessels and the urinary bladder.

1. Igawa, Y. et al. (1999) British journal of pharmacology 126, 819-25. PMID: 10188996
2. Emorine, LJ. et al. (1989) Science (New York, N.Y.) 245, 1118-21. PMID: 2570461
3. Candelore, MR. et al. (1996) Endocrinology 137, 2638-41. PMID: 8641219
4. Soeder, KJ. et al. (1999) The Journal of biological chemistry 274, 12017-22. PMID: 10207024
5. Gauthier, C. et al. (1998) The Journal of clinical investigation 102, 1377-84. PMID: 9769330
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human ADRB3 Antibody (SAA1577)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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