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Anti-Human VASH2/Vasohibin-2 Recombinant Antibody (SAA1602) (HP280013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HP280013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1602
靶标VASHL, Vasohibin-2, VASH2, Vasohibin-like protein, Tubulinyl-Tyr carboxypeptidase 2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q86V25
RRIDAnti-Human VASH2/Vasohibin-2 Antibody (SAA1602) (abinScience Cat# HP280013, RRID:AB_3727363)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Tubulinyl-Tyr carboxypeptidase 2 (VASH2/Vasohibin-2) is a ~40 kDa protein. Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtubule detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation.

1. Nieuwenhuis, J. et al. (2017) Science (New York, N.Y.) 358, 1453-1456. PMID: 29146869
2. Liao, S. et al. (2019) Cell research 29, 533-547. PMID: 31171830
3. Kimura, H. et al. (2009) Blood 113, 4810-8. PMID: 19204325
4. Wang, N. et al. (2019) Nature structural & molecular biology 26, 571-582. PMID: 31235911
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human VASH2/Vasohibin-2 Antibody (SAA1602)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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