

| 货号 | HC500013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1671 | ||||
| 靶标 | Myotubularin, Phosphatidylinositol-3, 5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTM1, CG2 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q13496 | ||||
| RRID | Anti-Human MTM1 Antibody (SAA1671) (abinScience Cat# HC500013, RRID:AB_3727432) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||
| 产品使用信息 |
| ||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Myotubularin (MTM1) is a ~69 kDa protein. Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. 1. Taylor, GS. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8910-5. PMID: 10900271 2. Blondeau, F. et al. (2000) Human molecular genetics 9, 2223-9. PMID: 11001925 3. Schaletzky, J. et al. (2003) Current biology : CB 13, 504-9. PMID: 12646134 4. Tsujita, K. et al. (2004) The Journal of biological chemistry 279, 13817-24. PMID: 14722070 5. Cui, X. et al. (1998) Nature genetics 18, 331-7. PMID: 9537414 6. Hnia, K. et al. (2011) The Journal of clinical investigation 121, 70-85. PMID: 21135508 7. Gupta, VA. et al. (2013) PLoS genetics 9, e1003583. PMID: 23818870 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human MTM1 Antibody (SAA1671)



24小时产品查询

扫一扫关注我们

专属渠道经理