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Anti-Human MTM1 Recombinant Antibody (SAA1671) (HC500013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HC500013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1671
靶标Myotubularin, Phosphatidylinositol-3, 5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTM1, CG2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q13496
RRIDAnti-Human MTM1 Antibody (SAA1671) (abinScience Cat# HC500013, RRID:AB_3727432)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Myotubularin (MTM1) is a ~69 kDa protein. Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture.

1. Taylor, GS. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8910-5. PMID: 10900271
2. Blondeau, F. et al. (2000) Human molecular genetics 9, 2223-9. PMID: 11001925
3. Schaletzky, J. et al. (2003) Current biology : CB 13, 504-9. PMID: 12646134
4. Tsujita, K. et al. (2004) The Journal of biological chemistry 279, 13817-24. PMID: 14722070
5. Cui, X. et al. (1998) Nature genetics 18, 331-7. PMID: 9537414
6. Hnia, K. et al. (2011) The Journal of clinical investigation 121, 70-85. PMID: 21135508
7. Gupta, VA. et al. (2013) PLoS genetics 9, e1003583. PMID: 23818870
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human MTM1 Antibody (SAA1671)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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