Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HS700013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1691

FAM132B, C1QTNF15, Erythroferrone, Complement C1q tumor necrosis factor-related protein 15, Myonectin, CTRP15, ERFE

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q4G0M1

Anti-Human ERFE Antibody (SAA1691) (abinScience Cat# HS700013, RRID:AB_3727452)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Erythroferrone (ERFE) is a ~37 kDa protein. Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Inhibits apoptosis and inflammatory response in cardiomyocytes via promotion of sphingosine-1-phosphate (S1P) and cAMP-dependent activation of AKT signaling. Inhibits autophagy induced by nutrient deficiency in hepatocytes via promoting the phosphorylation of IRS1, AKT, and MTOR, and thereby subsequent activation of the AKT-MTOR signaling pathway. Negatively regulates the differentiation of osteoblasts, potentially via sequestering BMP2, and thereby inhibits the activation of SMAD signaling.

1. Kautz, L. et al. (2014) Nature genetics 46, 678-84. PMID: 24880340

2. Arezes, J. et al. (2018) Blood 132, 1473-1477. PMID: 30097509

3. Wang, CY. et al. (2020) Blood 135, 453-456. PMID: 31800957

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

SDS-PAGE

SDS-PAGE for Anti-Human ERFE Antibody (SAA1691)

产品说明书

Anti-Human ERFE Recombinant Antibody (SAA1691).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ERFE Recombinant Antibody (SAA1691) (HS700013)

概述

图片

参考文献

产品说明书

相关产品推荐

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