Anti-Human DAB2IP Recombinant Antibody (SAA1697) (HV442013)

价格:

规格：

50ug
100ug
1mg

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

HV442013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1697

DOC-2/DAB-2 interactive protein, DAB2IP, KIAA1743, Disabled homolog 2-interacting protein, AF9Q34, AIP1, DAB2 interaction protein, DAB2-interacting protein, ASK-interacting protein 1, AIP-1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q5VWQ8

Anti-Human DAB2IP Antibody (SAA1697) (abinScience Cat# HV442013, RRID:AB_3727458)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Disabled homolog 2-interacting protein (DAB2IP) is a ~131 kDa protein. Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Also plays a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS). Modulates the balance between phosphatidylinositol 3-kinase (PI3K)-AKT-mediated cell survival and apoptosis stimulated kinase (MAP3K5)-JNK signaling pathways; sequesters both AKT1 and MAP3K5 and counterbalances the activity of each kinase by modulating their phosphorylation status in response to pro-inflammatory stimuli.

1. Luo, X. et al. (2017) Oncotarget 8, 85415-85427. PMID: 29156729

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human DAB2IP Antibody (SAA1697)

产品说明书

Anti-Human DAB2IP Recombinant Antibody (SAA1697).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DAB2IP Recombinant Antibody (SAA1697) (HV442013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DAB2IP Recombinant Antibody (SAA1697) (HV442013)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价