Anti-Human ACVR1C Recombinant Antibody (SAA1706) (HV040013)

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规格：

50ug
100ug
1mg

数量：

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概述
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参考文献
产品说明书

HV040013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1706

Activin receptor-like kinase 7, ALK7, ACVR1C, Activin receptor type IC, ALK-7, Activin receptor type-1C, ACTR-IC

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q8NER5

Anti-Human ACVR1C Antibody (SAA1706) (abinScience Cat# HV040013, RRID:AB_3727467)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Activin receptor type-1C (ACVR1C) is a ~54 kDa protein. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consists of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B, activin E and NODAL. Upon NODAL binding, activation results in increased apoptosis and reduced proliferation through suppression of AKT signaling and the activation of Smad2-dependent signaling pathway in pancreatic beta-cells, trophoblasts, epithelial or neuronal cells.

1. Xu, G. et al. (2004) The Journal of clinical endocrinology and metabolism 89, 5523-34. PMID: 15531507

2. Munir, S. et al. (2004) The Journal of biological chemistry 279, 31277-86. PMID: 15150278

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human ACVR1C Antibody (SAA1706)

产品说明书

Anti-Human ACVR1C Recombinant Antibody (SAA1706).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ACVR1C Recombinant Antibody (SAA1706) (HV040013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ACVR1C Recombinant Antibody (SAA1706) (HV040013)

概述

图片

参考文献

产品说明书

相关产品推荐

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