Anti-Human JAM3 Recombinant Antibody (SAA1837) (HP669013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP669013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1837

JAM-3, JAM-C, JAM-2, Junctional adhesion molecule 3, Junctional adhesion molecule C, sJAM-C, JAM3

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9BX67

Anti-Human JAM3 Antibody (SAA1837) (abinScience Cat# HP669013, RRID:AB_3727600)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Junctional adhesion molecule C (JAM3) is a ~35 kDa protein. Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM2 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating transmigration through the endothelium. Plays a role in spermatogenesis where JAM2 and JAM3, which are respectively expressed by Sertoli and germ cells, mediate an interaction between both cell types and play an essential role in the anchorage of germ cells onto Sertoli cells and the assembly of cell polarity complexes during spermatid differentiation.

1. Arrate, MP. et al. (2001) The Journal of biological chemistry 276, 45826-32. PMID: 11590146

2. Liang, TW. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 1618-26. PMID: 11823489

3. Arcangeli, ML. et al. (2014) Stem cells (Dayton, Ohio) 32, 1043-54. PMID: 24357068

4. Santoso, S. et al. (2002) The Journal of experimental medicine 196, 679-91. PMID: 12208882

5. Zen, K. et al. (2004) Molecular biology of the cell 15, 3926-37. PMID: 15194813

6. Akawi, NA. et al. (2013) Human mutation 34, 498-505. PMID: 23255084

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human JAM3 Antibody (SAA1837)

产品说明书

Anti-Human JAM3 Recombinant Antibody (SAA1837).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JAM3 Recombinant Antibody (SAA1837) (HP669013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JAM3 Recombinant Antibody (SAA1837) (HP669013)

概述

图片

参考文献

产品说明书

相关产品推荐

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