Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HA935013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1857

SCN11A, hNaN, SNS2, PN5, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, SCN12A, Sodium channel protein type 11 subunit alpha, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9UI33

Anti-Human SCN11A Antibody (SAA1857) (abinScience Cat# HA935013, RRID:AB_3727620)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Sodium channel protein type 11 subunit alpha (SCN11A) is a ~204 kDa protein. Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization.

1. Dib-Hajj, SD. et al. (1999) FEBS letters 462, 117-20. PMID: 10580103

2. Blum, R. et al. (2002) Nature 419, 687-93. PMID: 12384689

3. Leipold, E. et al. (2013) Nature genetics 45, 1399-404. PMID: 24036948

4. Huang, J. et al. (2014) Brain : a journal of neurology 137, 1627-42. PMID: 24776970

5. Han, C. et al. (2015) Neuromolecular medicine 17, 158-69. PMID: 25791876

6. Leipold, E. et al. (2015) Nature communications 6, 10049. PMID: 26645915

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human SCN11A Antibody (SAA1857)

产品说明书

Anti-Human SCN11A Recombinant Antibody (SAA1857).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

概述

图片

参考文献

产品说明书

相关产品推荐

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