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Anti-Human ADGRG2/GPR64 Recombinant Antibody (SAA1866) (HA124013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HA124013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1866
靶标Adhesion G-protein coupled receptor G2, HE6, TM7LN2, Human epididymis-specific protein 6, ADGRG2, He6, G-protein coupled receptor 64, GPR64
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q8IZP9
RRID

Anti-Human ADGRG2/GPR64 Antibody (SAA1866) (abinScience Cat# HA124013, RRID:AB_3727629)
_x005F_x000D_

状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Adhesion G-protein coupled receptor G2 (ADGRG2/GPR64) is a ~111 kDa protein. Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as dehydroepiandrosterone (DHEA; also named 3beta-hydroxyandrost-5-en-17-one) and androstenedione. Involved in a signal transduction pathway controlling epididymal function and male fertility. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG2 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Also able to couple with G(q) G proteins in vitro.

1. Zhang, DL. et al. (2018) eLife 7. PMID: 29393851
2. Lin, H. et al. (2022) Nature chemical biology 18, 1196-1203. PMID: 35982227
3. Yang, Z. et al. (2025) Cell 188, 1589-1604.e24. PMID: 39884271
4. Sun, Y. et al. (2021) The Journal of biological chemistry 296, 100174. PMID: 33303626
5. Gad, AA. et al. (2021) Scientific reports 11, 14060. PMID: 34234254
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human ADGRG2/GPR64 Antibody (SAA1866)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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