Anti-Human NMES1 Recombinant Antibody (SAA1899) (HA194013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HA194013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1899

Protein FOAP-11, C15orf48, NMES1, Normal mucosa of esophagus-specific gene 1 protein

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9C002

Anti-Human NMES1 Antibody (SAA1899) (abinScience Cat# HA194013, RRID:AB_3727663)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Cytochrome c oxidase associated subunit FA4L3 (NMES1) is a ~9 kDa protein. Mitochondrial small peptide that orchestrates a two-pronged immunoregulatory mechanism in response to inflammatory stimuli. Replaces the canonical cytochrome c oxidase subunit COXFA4 in mitochondrial complex IV and targets it to degradation, attenuating mitochondrial respiration, reducing membrane potential as well as ROS generation and modulates innate immune signaling. Additionally, initiates stress-independent autophagy by lowering ATP levels, activating AMPK-ULK1 signaling, boosting glutathione production, and thereby mitigating oxidative stress and supporting immune tolerance.

1. Lee, CQE. et al. (2021) Nature communications 12, 2130. PMID: 33837217

2. Clayton, SA. et al. (2021) Science advances 7, eabl5182. PMID: 34878835

3. Takakura, Y. et al. (2024) Nature communications 15, 953. PMID: 38296961

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human NMES1 Antibody (SAA1899)

产品说明书

Anti-Human NMES1 Recombinant Antibody (SAA1899).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NMES1 Recombinant Antibody (SAA1899) (HA194013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NMES1 Recombinant Antibody (SAA1899) (HA194013)

概述

图片

参考文献

产品说明书

相关产品推荐

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