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Anti-Human BPIFA1/LunX Recombinant Antibody (SAA1910) (HA021013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HA021013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1910
靶标Von Ebner protein Hl, SPLUNC1, Palate lung and nasal epithelium clone protein, PLUNC, SPURT, Lung-specific protein X, Tracheal epithelium-enriched protein, BPI fold-containing family A member 1, BPIFA1, Secretory protein in upper respiratory tracts, Nasopharyngeal carcinoma-related protein, LUNX, Short PLUNC1, NASG
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9NP55
RRID

Anti-Human BPIFA1/LunX Antibody (SAA1910) (abinScience Cat# HA021013, RRID:AB_3727674)
_x005F_x000D_

状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

BPI fold-containing family A member 1 (BPIFA1/LunX) is a ~26 kDa protein. Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants.

1. Ning, F. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 5349-60. PMID: 25223608
2. Sayeed, S. et al. (2013) Infection and immunity 81, 285-91. PMID: 23132494
3. Liu, Y. et al. (2013) The American journal of pathology 182, 1519-31. PMID: 23499554
4. Walton, WG. et al. (2016) Biochemistry 55, 2979-91. PMID: 27145151
5. Garland, AL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15973-8. PMID: 24043776
6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190
7. Lindahl, M. et al. (2001) Electrophoresis 22, 1795-800. PMID: 11425234
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human BPIFA1/LunX Antibody (SAA1910)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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