Anti-Human SCUBE2 Recombinant Antibody (SAA1911) (HA065013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HA065013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1911

Signal peptide, CUB and EGF-like domain-containing protein 2, SCUBE2, Protein CEGP1, Scube/You, CEGP1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NQ36

Anti-Human SCUBE2 Antibody (SAA1911) (abinScience Cat# HA065013, RRID:AB_3727675)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2) is a ~109 kDa protein. Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane. Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface. Synergizes with DISP1 to increase SHH secretion. Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis.

1. Creanga, A. et al. (2012) Genes & development 26, 1312-25. PMID: 22677548

2. Tukachinsky, H. et al. (2012) Cell reports 2, 308-20. PMID: 22902404

3. Jakobs, P. et al. (2014) Journal of cell science 127, 1726-37. PMID: 24522195

4. Lin, YC. et al. (2017) Arteriosclerosis, thrombosis, and vascular biology 37, 144-155. PMID: 27834687

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human SCUBE2 Antibody (SAA1911)

产品说明书

Anti-Human SCUBE2 Recombinant Antibody (SAA1911).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SCUBE2 Recombinant Antibody (SAA1911) (HA065013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SCUBE2 Recombinant Antibody (SAA1911) (HA065013)

概述

图片

参考文献

产品说明书

相关产品推荐

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