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Anti-Human TMEM106B Recombinant Antibody (SAA1912) (HA136013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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  • 参考文献

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概述
货号HA136013
品牌abinScience
种属反应性Human, Mouse
应用ELISA, FCM, SPR
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1912
靶标TMEM106B, Transmembrane protein 106B
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9NUM4, Q80X71
RRID

Anti-Human TMEM106B Antibody (SAA1912) (abinScience Cat# HA136013, RRID:AB_3727676)
_x005F_x000D_

状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Transmembrane protein 106B (TMEM106B) is a ~31 kDa protein. In neurons, involved in the transport of late endosomes/lysosomes. May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking. May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites.

1. Stagi, M. et al. (2014) Molecular and cellular neurosciences 61, 226-40. PMID: 25066864
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human TMEM106B Antibody (SAA1912)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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