Anti-Human PD-L1 Recombinant Antibody (405.9A11) (HV974093)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HV974093

abinScience

种属反应性

Human

IHC, WB

Mouse

Monoclonal

405.9A11

B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1

内毒素水平

< 10 EU/mg

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9NZQ7

Anti-Human CD274/PD-L1/B7-H1 Antibody (405.9A11) (abinScience Cat# HV974093, RRID:AB_3729397)

Liquid

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

B-lymphocyte antigen CD19 (CD274/PD-L1) is a ~61 kDa protein. Functions as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. CD274 is the therapeutic target of atezolizumab (Tecentriq) and durvalumab (Imfinzi).

1. Vanshylla, K. et al. (2018) Scientific reports 8, 4244. PMID: 29523808

2. Carter, RH. et al. (1992) Science (New York, N.Y.) 256, 105-7. PMID: 1373518

3. van Zelm, MC. et al. (2006) The New England journal of medicine 354, 1901-12. PMID: 16672701

4. de Rie, MA. et al. (1989) Cellular immunology 118, 368-81. PMID: 2463100

5. Wang, Y. et al. (2002) Immunity 17, 501-14. PMID: 12387743

6. Sato, S. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 3278-87. PMID: 9317126

7. Buhl, AM. et al. (1997) The Journal of experimental medicine 186, 1897-910. PMID: 9382888

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

SDS-PAGE

SDS-PAGE for Anti-Human CD274/PD-L1/B7-H1 Antibody (405.9A11)

产品说明书

Anti-Human PD-L1 Recombinant Antibody (405.9A11).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PD-L1 Recombinant Antibody (405.9A11) (HV974093)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PD-L1 Recombinant Antibody (405.9A11) (HV974093)

概述

图片

参考文献

产品说明书

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