Anti-Human ANAPC2 Recombinant Antibody (SAA2123) (HA840013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HA840013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

IgG2a

SAA2123

ANAPC2, anaphase promoting complex subunit 2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9UJX6

Anti-Human ANAPC2 Antibody (SAA2123) (abinScience Cat# HA840013, RRID:AB_3729475)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Anaphase-promoting complex subunit 2 (ANAPC2) is a ~93 kDa protein. Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.

1. Tang, Z. et al. (2001) Molecular biology of the cell 12, 3839-51. PMID: 11739784

2. Jin, L. et al. (2008) Cell 133, 653-65. PMID: 18485873

3. Yau, RG. et al. (2017) Cell 171, 918-933.e20. PMID: 29033132

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human ANAPC2 Antibody (SAA2123)

产品说明书

Anti-Human ANAPC2 Recombinant Antibody (SAA2123).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ANAPC2 Recombinant Antibody (SAA2123) (HA840013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ANAPC2 Recombinant Antibody (SAA2123) (HA840013)

概述

图片

参考文献

产品说明书

相关产品推荐

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